1, heart disease patients: it is generally believed that heart disease patients with the following conditions should not get pregnant. (1) heart function grade 3-4; (2) history of heart failure; (3) severe mitral stenosis, frequent shortness of breath and hemoptysis; (4) rheumatic activities such as arthralgias, fever, accelerated blood sedimentation, etc.; (5) significant enlargement of the heart; (6) simultaneous combination of multiple systemic diseases such as nephritis, tuberculosis, etc.; (7) history of previous heart emboli dislodged causing embolism of small vessels in the brain, kidney or fundus of the eye; anemic heart disease hemoglobin <50g/L; (8) hypertensive heart disease; (9) viral myocarditis, etc. 2, hypertensive patients: patients with intermediate and advanced hypertension should not get pregnant, even if they can get pregnant with early hypertensive patients, they should be alert to the occurrence of hypertensive disease during pregnancy. 3, hepatitis patients: patients with acute hepatitis can not be married, should wait until the condition has improved before considering pregnancy. 4, patients with nephritis: patients with nephritis should not get pregnant. If the disease has basically recovered, blood pressure is normal, urine protein trace or occasionally "+", normal kidney function before pregnancy, but should also regulate prenatal examination. 5, tuberculosis patients: patients with severe and active tuberculosis can never get pregnant. Only those who have recovered from tuberculosis can become pregnant. 6, diabetic patients: diabetic patients, especially those with significant nephropathy or severe retinopathy should not be pregnant. 7, asthma patients: patients with long-term chronic asthma and severely impaired cardiopulmonary function should not get pregnant. 8, leukemia patients: pregnancy can lead to leukemia patients with immune deficiency and aggravation of the disease. Therefore, patients with leukemia should not get pregnant, and once pregnant, abortion should be performed. 9, hyperthyroidism patients: pregnancy can aggravate the condition of hyperthyroidism patients, heart failure, hyperthyroidism crisis. In addition, patients with hyperthyroidism in pregnancy are at increased risk of miscarriage, preterm delivery, stillbirth, hyperemesis, postpartum hemorrhage and postpartum infection. Therefore, patients with severe hyperthyroidism and untreated hyperthyroidism should not become pregnant.