Hepatitis B 245 refers to Hepatitis B Surface Antibody, Hepatitis B E Antibody and Hepatitis B Core Antibody, and all three of them are positive, and it is usually possible to donate blood. Hepatitis B surface antibody, Hepatitis B E antibody and Hepatitis B core antibody are positive, which indicates that you have been infected with Hepatitis B, but now the virus has been cleared and protective antibodies have been formed in your body. In this case, donating blood will not have any effect on the body and will not affect the liver function, and it fully meets the standard of blood donation, and will not cause the transmission of hepatitis B. After donating blood, you should pay attention to your body and observe the condition of your body. After donating blood, you should pay attention to observe your physical condition, if you feel weak, or have symptoms such as panic, shortness of breath, drowsiness, sleepiness, etc., it is generally not recommended to donate blood, and if necessary, you should seek medical treatment in time.