Most children with Kawasaki disease recover well in later stages, while a few may relapse, and some children with post-coronary sequelae may require long-term follow-up and monitoring. Kawasaki disease, also known as pediatric cutaneous mucocutaneous lymph node syndrome, is an acute systemic vasculitis disease that occurs in children and infants. It is a self-limiting disease that often stops automatically after a certain degree of development and gradually recovers, and the majority of patients can recover completely after regular treatment. Since the cause of Kawasaki disease is unknown, it is difficult to completely eradicate the disease, and a few children may have relapses, even multiple relapses. In some children with Kawasaki disease, the disease may involve the cardiovascular system, resulting in coronary artery disease, decreased myocardial contractility, heart failure, myocardial infarction, cardiac arrhythmia, peripheral arterial occlusion, and other secondary pathologies, which have a poor prognosis and require lifelong follow-up. If Kawasaki disease is diagnosed, please follow the doctor’s instructions for treatment.