The survival period of patients with advanced lung squamous cancer cannot be generalized and needs to be further analyzed according to the patient’s physical status and sensitivity to therapeutic drugs. Patients with advanced squamous lung cancer have lost the chance of radical resection surgery and can only undergo palliative therapies such as radiotherapy and chemotherapy. If patients with advanced lung squamous carcinoma have not yet developed distant metastases, such as liver metastases or brain metastases, and can cooperate with palliative treatment, the survival period of patients is usually about 1-2 years. However, if the patient is not sensitive to radiotherapy or chemotherapy, premature intracranial metastasis, intrahepatic metastasis, or intrapulmonary metastasis causing obvious respiratory dysfunction in both lungs, then the patient’s survival is mostly limited to within half a year, and may even be only within 3 months. Patients with advanced squamous lung cancer should maintain a good attitude and actively cooperate with doctors in order to prolong survival time and improve life quality.