What was the first immunologic drug to treat squamous lung cancer?

Lung squamous carcinoma, also known as squamous epithelial cell carcinoma of the lung, including spindle cell carcinoma, is the most common type, accounting for 40% to 51% of primary lung cancers. Lung squamous carcinoma is most common in elderly men and is closely related to smoking. Lung squamous carcinoma is most common in central lung cancer, and has the tendency to grow in the chest tube cavity. Early stage of lung squamous carcinoma often triggers bronchial stenosis, or obstructive pneumonia. Lung squamous carcinoma grows slowly, metastasizes late, has more chances of surgical resection and higher 5-year survival rate. Lung squamous carcinoma is not as sensitive to radiotherapy and chemotherapy as small-cell undifferentiated carcinoma. Chemotherapy: The first cycle of chemotherapy for squamous lung cancer is more sensitive, and the therapeutic effect can be up to 25%, the second cycle of chemotherapy can be up to 10%, and the effect is basically zero after three cycles. Chemotherapy will inhibit bone marrow hematopoietic system, mainly the decline of white blood cells and platelets, which can be treated with granulocyte colony-stimulating factor and platelet-stimulating factor. Chemotherapy is divided into therapeutic chemotherapy and adjuvant chemotherapy. Radiotherapy has the best curative effect on small cell lung cancer, followed by squamous cell carcinoma and adenocarcinoma. Squamous cell carcinoma has moderate sensitivity to rays, and the lesions are mainly localized invasion and relatively slow metastasis, so it is mostly treated with radical therapy. The combination of radiotherapy and chemotherapy can depend on the different conditions of patients, and synchronous radiotherapy or alternating chemo-radiotherapy can be adopted. Surgical treatment Surgical treatment is the first choice and the most important treatment method for squamous lung cancer, which can achieve the purpose of cure for early squamous lung cancer patients.