In addition to liver function tests, patients with hepatitis B major triple yang should be further tested for hepatitis B virus quantification and liver ultrasound, and after comprehensive evaluation based on the test results, clinicians can determine whether to use medication. Patients who are older than 30 years old and whose hepatitis B virus quantification is >20,000 IU/L can be treated or not based on elevated transaminases or liver puncture pathology; patients with a family history of hepatitis B-induced liver cancer or cirrhosis should be closely monitored and given antiviral treatment in a timely manner. If the hepatitis B virus is active again and liver lesions are not detected in time and treated accordingly, they will develop into cirrhosis, ascites or even liver cancer. Since most of the patients with hepatitis B major tri-positive have no obvious clinical symptoms, only a few have symptoms such as discomfort, vague pain, weakness and loss of appetite in the liver (under the right side of the chest, rib-covered area), and liver function is normal, it is easy to be ignored, so it must be taken seriously. Therefore, patients with hepatitis B major tri-positive need treatment in most cases even if their liver function is normal, and they must cooperate with their doctors to improve the relevant tests so as not to delay their condition.