What is the most effective way to treat diabetic foot? I have already given a chat about the treatment method a long time ago and pointed out that the reason why many patients are never cured is related to the improper choice of method. So, what method is effective? In fact, as long as the method is the right one and the treatment is based on the disease, the method is effective. Here, let’s first understand the diabetic foot and its causes. Diabetic foot is a complication of diabetes, and the earliest cause is definitely due to high blood sugar. But high blood sugar is not direct, if high blood sugar causes nerve and blood vessel damage, plus trauma, are the three main causes of early diabetic foot. After the later infection, another etiological infection is added. To this point, effective treatment methods must target different etiologies. First, for blood sugar control. High blood sugar in the wound, high osmotic pressure inside and outside the cells, cells are prone to lose a lot of water nutrients, and the immunity and resistance of cells are reduced, which increases the risk of infection. However, it does not mean that only when the blood sugar is controlled smoothly can we do other treatment, which is easy to delay the best treatment time. Second, the treatment of lower limb ischemia. In particular, vascular surgery advocates intervention or stenting to unblock the blood vessels, or bone removal surgery to improve circulation, I personally do not advocate bone removal, but for vascular surgery treatment should be a comprehensive assessment of the patient’s physical condition. Vascular surgery is effective for large vessels, but for small vessels below the knee and distal to the knee, the official cavity is too small to achieve the desired treatment purpose. I recommend the treatment of peripheral vascular disease using a combination of Chinese and Western medicine to rebuild the collateral circulation and improve microcirculation to increase the oxygen saturation of the lower limbs. Third, for the treatment of neuropathy. Nerves play an important role in muscle contraction and movement of the lower limbs, and the lack of nerve function is not conducive to the treatment and recovery of muscle function. However, it is difficult to restore the nerve to its original condition, so the main goal of treatment is to nourish the nerve and control the aggravation of the lesion. Fourth, for trauma. Trauma may not necessarily cause infection, but can increase the risk of infection, especially wounds with improper care treatment and combined ischemia of the lower limbs. Therefore, once the wound appears to go to the hospital to seek professional medical treatment. Fifth, the treatment of infection. In fact, the most fearful thing about diabetic foot treatment is that the infection cannot be controlled, the germs will gradually erode the healthy tissue, more cells break down, the health loss is greater, a large number of toxins are absorbed by the body, easy to break the metabolic balance, and eventually organ failure is possible. To control the infection, one of the important steps is timely debridement, cleaning out the infected necrotic muscle, blood vessels, tendons and bone, etc., which can reduce the germ load and improve the chances of controlling the infection, while also creating conditions for fresh wound growth. Finally, it is emphasized that several of the above etiologies are not isolated, but interact with each other to influence each other. In addition to this there is the physical condition of the patient, such as age, psychology, cardiovascular disease and other physical qualities, which all have an impact on gangrene. Therefore, the treatment of diabetic foot must be comprehensive and holistic, and a plan must be developed for any cause that could potentially affect the treatment to improve the overall outcome.