Urine protein 1 +, clinical can be written as urine protein 1 + or urine protein (+), the specific meaning of what represents depends on the actual situation. Generally speaking if once in a while it is urine protein 1+, it may be that the test sample is contaminated; if the retest result is also urine protein 1+, it may be related to kidney disease.1. If the urine protein test, only once 1+, is normal after the retest, it suggests that the kidney problem is not serious, probably due to inaccurate retention of urine or concentrated urine, resulting in a single urine protein 1+. It is often seen clinically that the patient has a false positive urine protein due to retention of non-clean middle urine, or vaginal secretions and semen contamination, and the kidneys actually have no problems; 2. Repeated urine protein 1+ is highly suggestive of kidney disease. For example, various acute glomerulonephritis, chronic glomerulonephritis, acute progressive nephritis, interstitial nephritis, hypertensive nephropathy, etc. Urine protein 1+, suggesting that the amount of proteinuria is not too large, it is recommended to improve urine and blood tests. Urine examination includes 24h urine protein quantification, urine protein molecular weight determination, urine microalbumin/creatinine, etc. In blood, we need to improve the anti-nuclear antibody, hepatitis B and C infection index, immunoglobulin, complement and immune antibody, etc. to clarify the specific source and cause of proteinuria, and if necessary, kidney puncture biopsy is needed to clarify the diagnosis and decide the next step of treatment. Therefore, if there is urine protein 1+, it is recommended to adjust the diet, reduce the protein intake, ensure sufficient rest and have a review. If the result of the recheck is still urine protein 1+, you should go to the hospital in time to get a clear diagnosis and active treatment.