Patients with anal fissures presenting with significant perianal itching can apply topical erythromycin ointment after cleaning the anus. Erythromycin ointment belongs to the macrolide class of antimicrobials, is inexpensive and easy to use, and topical application has an isolating and anti-infective effect. For anal fissures, you should actively treat constipation because the main triggering factor is habitual constipation. Each bowel movement can lead to aggravation of fissures, bleeding, and even infection, so you should pay attention to local hygiene and promptly cleanse after each bowel movement. In addition, adhere to the daily application of warm salt water sitz bath, but also with the application of hemorrhoid cream, you can choose Ma Yinglong hemorrhoid cream or anal tide cream, local medication can also reduce the symptoms. You should pay attention to the regularity of your life, not to strain, and you can do sports exercises and contraction of the anal raphe muscle, which can also relieve the local condition.