Severe superficial gastritis with erosion and a small amount of glandular intestinal epithelial hyperplasia is a precancerous lesion with a tendency to become cancerous, which can be reversed if timely treatment is carried out. Severe superficial gastritis with erosion indicates that atrophic gastritis has occurred, accompanied by a small amount of intestinal epithelialization, which is precancerous and has the risk of gastric cancer, and can be reversed if timely treatment is given; if no treatment is given, it may develop into gastric cancer. Generally, short-term or long-term intermittent treatment is carried out, including the use of omeprazole, lansoprazole, amoxicillin, bismuth potassium citrate and other drugs, as well as supplementing appropriate amount of vitamins, selenium-containing medicines and so on, and the medicines need to be used under the guidance of doctors. It is recommended that patients seek timely medical treatment, standardized treatment under the guidance of doctors.