Most of the vaccines such as the new crown vaccine and rabies vaccine can be administered to 15-year-olds after relevant contraindications have been ruled out; adolescents in special states need to be analyzed according to their conditions. 1. Healthy 15-year-olds: when they are 15 years old, the vaccines prescribed by the state such as DPT have basically been completed; for rabies vaccine, tetanus vaccine, etc., if there is no contraindication, they can be vaccinated when there is a high risk of infection; for the prevention of infectious diseases, such as new coronavirus vaccine, it can be vaccinated, and it is recommended that they be vaccinated in a timely manner. 2.Contraindications to vaccination for 15-year-olds (1) Vaccination is prohibited during the active period of infectious diseases such as colds, gastrointestinal infections, and rheumatic immune diseases. (2) Allergy to vaccine components is prohibited. (3) Vaccination is prohibited when epilepsy is not under control or during the acute stage of severe neurological diseases such as Guillain-Barré syndrome. 3.Vaccination for people with special status at 15 years of age (1) Allergic diseases such as food allergy, allergic rhinitis in remission, asthma in remission, etc. can be vaccinated normally when their health condition is stable. (2) Congenital diseases such as congenital hypothyroidism, Down’s syndrome and congenital heart disease can be vaccinated normally. (3) Stable epilepsy without seizures for more than 6 months, and other neurological diseases with stable conditions, can be vaccinated normally. Whether vaccination is possible or not, it is recommended to go into a professional medical institution to make a decision after a comprehensive consultation and necessary examination; please go to a professional medical institution for vaccination.