It is generally impossible for patients to lose weight successfully to make the three highs as well. For hypertension, hyperlipidemia and hyperglycemia, besides being related to obesity, they are also influenced by various factors such as genetic factors, and weight loss only reduces one risk factor. For patients with three highs, it is recommended to give lifestyle improvements, pay attention to monitoring blood pressure, blood sugar and blood lipids, and supplement with the application of antihypertensive, hypoglycemic and lipid-lowering drugs. Weight loss can be used to assist in lowering blood pressure, and attention needs to be paid to monitoring the improvement of related indicators, and the application of related drugs can be reduced if necessary, but one cannot rely solely on weight loss to remove all risk factors and thus make the three highs disappear completely.