The skull is one of the hardest bone tissues in the human body, which plays a very important role in supporting and protecting the brain and head and facial organs, and is of great importance to the life of the whole body. Therefore, if cranial defect occurs, it will cause great harm to the human body and may even be life-threatening. Therefore, the skull defect should be repaired by using artificial skull material in time. Then some patients ask, “Is there any effect on the body when replacing the artificial skull? Cranial repair surgery is a routine surgical procedure to repair skull defects caused by various reasons, using certain artificial materials to repair the defective area. For patients with skull defects, the use of artificial skull bone for skull repair surgery has only good effects and no bad effects. If a patient has a cranial defect, first of all, it will be very unsafe, and if he or she is bumped or attacked by the outside world, it is likely to injure the brain tissue and even have a life-threatening effect; moreover, the cranial defect also makes the intracranial environment change, the intracranial pressure is unstable, and the cerebrospinal fluid circulation, blood circulation and the normal operation of neurological function in the cranium will be disturbed and disrupted, causing a series of cranial defect syndrome; in addition The cranial defect also makes the appearance of human head abnormal and unattractive, and may cause the patient’s psychological inferiority and imbalance. Therefore, it is very important to repair the skull in time, and the replacement of artificial skull has no bad effect on human body. Zhang, an 18-year-old high school student from Shanxi, suffered a serious cranial injury in a car accident and was left with a cranial defect in the left temporal parieto-occipital area after a craniotomy in a local hospital, which had a very bad effect on him, causing frequent dizziness and headaches, serious collapse of the scalp and unattractive appearance. After a detailed scientific diagnosis and evaluation, the team collected the 3D data of his skull, customized the peek material, and successfully performed peek cranioplasty for him, restoring his intact skull, relieving his dizziness and headache, and improving his mental condition, with ideal results. Our team widely uses the new polyetheretherketone peek material with excellent performance, and our team constantly carries out technical innovation and upgrade and material optimization design, and innovatively introduces the concept of aesthetic plastic surgery, while carrying out comprehensive peek cranioplasty, which can not only complete the repair of the skull, but also protect the muscle, blood vessel and nerve tissue, guarantee the perfection of all functions, and guarantee the aesthetic appearance. The results and clinical feedback are excellent.