Prostate cancer is more prevalent in older men, with the age of prevalence above 60 years. With the improvement of living standard and longer life expectancy, the incidence of prostate cancer in China has a tendency to continue to increase. For early stage prostate cancer, the main treatment method is radical surgery or radical radiotherapy. Although the use of ultrasound and prostate-specific antigen (PSA) has greatly improved the early diagnosis of prostate cancer, there are still many patients who are diagnosed at an advanced stage; or who cannot tolerate major surgery due to their age and the combination of other serious medical diseases, thus losing the opportunity of surgical treatment. Cryoablation treatment is in line with the characteristics of minimally invasive and safe medicine nowadays, and can achieve the effect of “good tumor elimination with low surgical risk”, which provides a new way out for patients with advanced and limited prostate cancer. Cryosurgery can kill the tumor cells in the target target through two freezing and rewarming processes. Cryoablation: Under the guidance of transrectal ultrasound or magnetic resonance, the doctor punctures the cryoablation probe to the lesion and starts the argon gas to cool it down, forming a very low temperature area below -100℃ in about 10 seconds, covering and wrapping the whole tumor tissue, causing the formation of ice crystals inside and outside the prostate cancer cells, resulting in ischemic necrosis of the tumor tissue and thus killing the tumor cells. Reheating: After 12-15 minutes, helium is activated again to instantly raise the temperature to 20℃, which dissolves the ice crystals inside the prostate cancer cells and causes them to rupture and die. II. What are the advantages of cryosurgery? Cryosurgery is a newly developed minimally invasive treatment technique abroad, which has been widely used in prostate cancer and kidney cancer in recent years. Compared with radical surgery and radiotherapy, its main advantages are: 1) Minimally invasive and safe, requiring only a small incision or insertion of a cryoprobe through the skin 2) Surgery minimizes complications such as pain and bleeding, and the patient recovers quickly 3) It is limited to the prostate or prostate gland and does not affect the surrounding tissues and organs too much 4) The surgery can be repeated and can be used to treat cancer that cannot be operated or treated because of age or other health problems 5. Very satisfactory results can be obtained in a suitable group of prostate cancer patients, with local control of the tumor, 5-year and 10-year survival rates similar to those of radical surgery and radiotherapy. Therefore, cryosurgery not only brings good results for patients with early stage limited prostate cancer, but also provides treatment opportunities for patients of advanced age and inoperable, which has a good development prospect and is a future direction for the treatment of prostate cancer.