Rheumatoid immune diseases are a group of diseases affecting bones, joints and surrounding soft tissues, such as tendons, bursae, and fascia, etc. They are a group of common and frequent diseases with diverse and complex etiologies, long duration and easy recurrence, and can be caused by infectious, immune, metabolic, endocrine, degenerative, geographic and environmental, and genetic causes. Rheumatic immune diseases are characterized by pain (joints, muscles, soft tissues, nerves, etc.) as the main symptom, and arthritis due to various causes accounts for an important part, but rheumatic immune diseases are not limited to arthritis. However, rheumatic immune diseases are not limited to arthritis, but they mainly involve lesions of bones, muscles, joints, and skin, and it is not uncommon to see multi-system damage caused by the involvement of internal organs. The term “connective tissue disease” or “collagen disease” used to be part of rheumatoid immune diseases, and they are not exactly the same as “rheumatoid immune diseases”. It is customary to refer to diffuse connective tissue diseases such as systemic lupus erythematosus, scleroderma, dermatomyositis, rheumatoid arthritis, desiccation syndrome, polyarteritis nodosa, Wegener’s granulomatosis, giant cell arteritis, and vasculitis as connective tissue diseases. The disease is a group of diseases based on the pathology of mucinous edema and fibrin-like degeneration of loose connective tissue. The etiology is not well understood, but is generally considered to be related to genetic, immune and viral infections, and is a multi-causal disease.