Kidney stones and urinary tract infections can be said to be in cahoots. On the one hand, kidney stones can block the urinary tract and lead to hydronephrosis, after which bacteria can multiply and cause serious urinary tract infections, leading to urinary urgency, frequent urination, high fever and, in serious cases, life-threatening, because bacteria can hide in the stones, so general anti-inflammatory drugs are not effective. On the other hand, after urinary tract infection, the pus urine produced by bacteria will wrap around the stones, causing them to get bigger and bigger, so forming a vicious circle. Therefore, a two-pronged approach to treatment is needed to remove the stones and keep the urinary tract open on the one hand, and to control the infection and destroy the bacteria on the other. The patient is a female, 50 years old, with high fever of 40° due to urinary tract infection, and the antibiotics applied in the local hospital were not effective. After admission, a stent tube was placed in the ureter to keep the urinary tract open, and the patient’s temperature dropped quickly. Finally, the kidney stones and ureteral stones were removed together by percutaneous nephrolithotomy, and the patient recovered and was discharged from the hospital. Pre-operative Intubation Post-operative Stone