Hepatitis B 5 145 positive should improve the hepatitis B virus DNA test, if necessary, should take antiviral drugs, such as entecavir. A positive item 145 of the Hepatitis B Penta is specifically a positive qualitative laboratory result for Hepatitis B surface antigen, Hepatitis B e antibody, and Hepatitis B core antibody, and is also commonly referred to as Hepatitis B Minor Triple Positive. This condition may be acute hepatitis B recovery or chronic hepatitis B infection. A positive test result of 145 of the five items of hepatitis B requires a complete examination of hepatitis B DNA, as well as liver function, abdominal ultrasound and other related tests. For patients with active viral replication, antiviral drugs such as entecavir should be given in time for standardized treatment, and the changes of hepatitis B 5 and hepatitis B DNA can be monitored during the treatment. The specific use of medication can be carried out under the guidance of specialists.