Aplastic anemia, referred to as reblastosis, is a bone marrow hematopoietic disorder with clinical manifestations of anemia, bleeding and infection. Aplastic anemia is mainly seen in young adults, and there are 2 peak incidence periods, namely the age group of 15-25 years old and the older age group of 60 years old and above. The incidence is slightly higher in men than in women. According to the severity of bone marrow failure and the progression of clinical course, they are classified into heavy and non-heavy reblasts and acute and chronic reblasts. The cause of aplastic anemia is caused by a decline in the immune function of the body, necrosis of hematopoietic stem cells and destruction of the hematopoietic microenvironment of the bone marrow. Clinical manifestations (1) Acute type of reanemia: hemorrhage, infection and fever, more than 60% have internal bleeding, mainly manifested as gastrointestinal bleeding, hematuria, fundus bleeding (often accompanied by visual impairment) and intracranial bleeding. Skin and mucosal bleeding is extensive and severe, and not easily controlled. Fever is almost always present during the course of the disease and is due to infection, often with necrotizing ulcers in the oropharynx and around the anus, leading to sepsis. Pneumonia is also common. (2) Chronic type of remittent disease: anemia, skin and mucous membrane bleeding, etc. Treatment Western medicine treatment: mainly rely on blood transfusion, hormone drugs, immune preparations and bone marrow transplantation, etc. Blood transfusion can temporarily increase the level of hemoglobin, but cannot play a curative role, and can temporarily relieve the disease; hormone drugs and immune preparations have significant effect in the early stage of treatment, but the later effect is poor, with a certain degree of dependence, and easy to relapse after stopping the drug; bone marrow transplantation is difficult to match, and there are risks in the operation, and the failure of matching before the work is abandoned. It is easy to relapse after surgery. The efficacy is unstable and the cost is high, and long-term application can cause many toxic side effects. Chinese medicine treatment: Different treatment principles and methods are used for different stages of the disease. For acute reoccurrence, the main treatment is to cool the blood and detoxify the toxin, while for chronic reoccurrence, the main treatment is to nourish the spleen and kidney, and to provide evidence-based care. In the acute stage, the main treatment is to clear heat and detoxify the toxin, cool the blood and stop bleeding, using Rhizoma Dihuang Tang with addition and subtraction. In the chronic stage, to strengthen the spleen, warm the kidney, and fill the marrow, Huangqi Jianzhong Tang and Yugui Wan should be used as an addition and subtraction. In the chronic stage, to strengthen the spleen and nourish the kidneys, to benefit the essence and nourish the blood, we use Dajingyuan Decoction with addition and subtraction.