The main components of corkage are glycerin and sorbitol, and its hypertonic effect allows water to penetrate into the intestine, which in turn softens the stool, stimulates the intestinal wall and eventually causes reflexive defecation. The onset of action of corkage is usually 5-10 minutes, and at most not more than half an hour. Of course, depending on the severity of the patient’s symptoms, the onset of action time varies. If the symptoms are mild, just because of the recent improper diet caused by poor bowel movement and dryness, it will generally take 3-5 minutes to take effect after use. For patients with slightly more severe symptoms, it usually takes 5-10 minutes to work. If the patient has occupying lesions in the abdominal cavity, such as intestinal tumors, constipation will be more serious, usually only once a week defecation, the use of open cork need to increase the dosage, generally 20-30 minutes after the use of the drug can take effect. For the specific use and usage of Cecropia, please refer to the clinical situation and wait for the doctor’s interview to guide the use of the medication. However, it is worth noting that, although Cecropia can relieve acute constipation, it is not recommended for long-term use. Because the main component of the open plug is glycerin, mainly to lubricate the intestinal tract, for the intestinal wall is a stimulating effect. If often stimulated will cause dependence, long-term enema may also lead to damage to the intestinal mucosa, so be sure to solve the problem of dry stool from the source.