Patients who have difficulty sleeping at night and waking up during the day need to adjust their biological clocks, which can be elaborated from the following two aspects: 1. Daytime: patients need to adjust their biological clocks, avoid sleeping during the day, and can do outdoor exercises, such as physical exercise, walking, running, etc.; 2. Nighttime: patients need to sleep and rest on time at night, and avoid the intake of stimulating drinks before and after dinner, such as strong tea and coffee, including stimulating food, it is recommended that patients consume easy-to-digest food for dinner. In addition to reduce external malignant stimuli, such as avoid looking at cell phones, computers, watching movies and other excitatory activities, can enter the sleep atmosphere and state faster. At the same time, you can take appropriate sleep-aiding drugs, such as Scholastin, Eszopiclone, Diazepam, to help patients fall asleep normally at night, so as to restore the biological clock.