Fingertip breakouts may be caused by physiological factors such as excessive dehydration of the skin, and to a lesser extent may be caused by diseases such as exfoliative keratolysis and herpes sweat. 1. Physiological factors: If the skin on the hands is excessively dehydrated, it may trigger the fingertips to break out. In addition, if the frequent use of soap and other supplies to clean the hands, may also trigger the fingertips burst skin. 2. Exfoliative Keratolysis: the disease often involves the hands and feet, clinical manifestations of peeling, scaling and other symptoms, often recurring. Its etiology is not yet clear, consider and ringworm rash, hyperhidrosis and genetic factors. 3. Sweat herpes: this disease often occurs in the hands and feet, mainly manifested as intense itching blisters, blisters absorbed after drying will appear peeling symptoms. The cause of this disease is not clear, may be hyperhidrosis, local allergies and mental factors. There are more reasons that trigger the skin bursting on the fingertips, after excluding the physiological factors, it is recommended that the patient go to the regular hospital for consultation to clarify the cause of the disease.