Sexuality is an important part of a couple’s life, as it is for people with hepatitis B. Although not all liver diseases affect the sexual function and sex life of patients, conditions such as heavy hepatitis, cirrhosis loss of compensation resulting in severe liver damage and hormonal imbalance can cause reduced sexual function and quality of sex life. It has been proven that the energy consumed by a person’s sexual life is equivalent to participating in a 100-meter sprint race. Such a large physical exertion is extremely detrimental to patients with liver disease who need rest. So what should a person with liver disease pay attention to in terms of sexual life? To prevent the spread of hepatitis B between husband and wife, the first thing is to meet each other sincerely, and the one who has the disease should tell the other party the real situation in time, so that the other party can also make “two-and-a-half” and liver function tests. If the other party is positive for any one of the “two pairs of half”, then the other party has also been infected with the hepatitis B virus, as long as the disease is not aggravated on the line. If the other party is negative for all five of these indicators, it means that he or she has not had hepatitis B and is not resistant to the hepatitis B virus. In this case, it is necessary to actively prevent, one of the spouses should not have sex during the acute hepatitis transmission period, the acute exacerbation of chronic hepatitis, and the active period. Hepatitis B is mainly transmitted through blood (e.g. blood transfusion, blood products, sharing needles, etc.). In addition, saliva, semen and vaginal secretions also contain some of the virus, so sexual contact is also a way of transmission. If the family members of hepatitis B patients are not infected and do not have antibodies, they should go to the hospital in time to get vaccinated and produce antibodies, which can play a good preventive role. In addition to blood transmission, sexual transmission is also one of the ways of transmission of hepatitis B. Therefore, the use of condoms can reduce the chance of contracting hepatitis B to a great extent. During the acute hepatitis period, when the alanine aminotransferase (ALT) is significantly elevated and symptoms such as general weakness and jaundice are obvious, any sexual activity, including masturbation, should be prohibited. To avoid overexertion and aggravation of the disease. At the same time, in acute hepatitis or chronic hepatitis active period, patients with liver disease are contagious and can expose their sexual partners to hepatitis infection through sexual contact. When acute hepatitis reaches clinical cure, chronic hepatitis basically reaches the standard of cure, the condition is stable for more than half a year can have sex; acute hepatitis clinical cure after a year of follow-up without abnormalities, chronic hepatitis observation for 2 years without abnormalities can be competent to work, can have a normal sex life. Chronic hepatitis, cirrhosis patients due to the impact of the disease, the general sexual desire are relatively indifferent, at this time should not be reluctant to make it difficult, but should follow the nature. When the liver disease is controlled, the body’s sex hormone metabolism is adjusted and restored to normal, sexual function can also be improved accordingly. HBsAg carriers can have a moderated sex life, consciously control the frequency of sex, but not indulge, otherwise it is easy to cause liver disease outbreaks or aggravation. The frequency of sexual life is generally 1-2 times a week for young people, once every 1-2 weeks for middle-aged people, and 1-2 times a month in late middle age. Most patients with alcoholic and fatty liver disease do not have obvious symptoms, half of them have liver discomfort, bloating, loss of appetite, erectile dysfunction, menstrual disorders, abnormal breast development, etc., a few people with mild abnormal liver function, there is no need to abstain from sex, in the liver function abnormalities should be temporarily abstained for a period of time, when liver function recovery can be moderate sex life.