How can pregnant women with hepatitis B safely survive pregnancy? Pregnant women with hepatitis B have an increased burden on the liver during pregnancy, and fatigue, bleeding, surgery and anesthesia during delivery can all aggravate liver damage. In addition, the production of endogenous estrogens, which must be inactivated in the liver, is significantly increased during pregnancy, and undoubtedly adds to the burden on the liver. In patients with cirrhosis, upper gastrointestinal bleeding is likely to occur due to increased plasma volume and cardiac output during pregnancy, and because the whole body is in a “diluted” state during pregnancy, the serum albumin level is relatively low, and edema, ascites and peritonitis are likely to occur. The burden of pregnancy on the liver increases with the number of weeks of gestation, and the risk of impaired or aggravated liver function increases. Therefore, the liver function of pregnant women must be tested throughout pregnancy, usually every one to two months, and once abnormalities are detected, a specialist should be consulted to deal with them. The following points should be noted by pregnant women: 1, pay attention to rest and nutrition, especially when hepatitis is active, more emphasis on bed rest, more high-quality protein diet, such as milk, fish, chicken, lean meat, etc., and a high vitamin diet, such as vegetables, fruits, etc. 2, must be under the guidance of the doctor to use drugs, especially before 12 weeks of pregnancy, because the fetus important organs are not yet mature, inappropriate use of drugs may cause damage to the fetus. In case of active hepatitis , the liver condition of the pregnant woman must be evaluated. If only alanine transaminase is elevated and no jaundice is present, vitamin supplements can be given on the basis of rest and nutrition. If there is recurrent nausea and vomiting (excluding that it is an early pregnancy reaction), or jaundice or even ascites, hospitalization in a specialized hospital is mandatory. 3, due to the high susceptibility of pregnant patients to hepatitis E virus, infection with hepatitis E virus in mid to late pregnancy is prone to develop into severe hepatitis with a morbidity and mortality rate of 10% to 20%, at the same time, hepatitis E virus infection can contribute to the activity of hepatitis B and further aggravate the disease. Since hepatitis E virus is transmitted orally, especially when eating unclean and uncooked shellfish, it is easy to be infected, so the intake of such food should be avoided.