Rectal cancer suggests 6 times of chemotherapy, which can not judge the staging, and the specific situation should be analyzed with the patient’s own condition. Rectal cancer is a common malignant tumor of intestinal tract, which is mostly caused by bad dietary habits, gene mutation, heredity and other factors. The main treatment method after diagnosis is surgical resection. In order to improve the surgical resection rate and eliminate the residual lesions, preoperative neoadjuvant chemotherapy and postoperative adjuvant chemotherapy are often carried out, which usually requires 6~8 times. Commonly used drugs for chemotherapy include 5-fluorouracil, capecitabine, etc., which should be applied under the guidance of doctors. Therefore, 6 times of chemotherapy can not determine the stage, the judgment of the stage needs to be combined with the degree of infiltration of the primary tumor, lymph node metastasis, whether distant metastasis occurs, rather than based on the number of chemotherapy.