Can warts cause cancer?

  There are many patients who believe that warts are only caused by low-risk HPV and are only benign growths that do not lead to skin cancer. In fact, such a view is wrong.  There are several different subtypes of human papillomavirus (HPV) that cause warts, the common ones being types 6, 11, 16, 18 and 33. Some of them only cause benign proliferation of epithelial cells, for HPV type 6, 11, called low-risk type (low-risk type); some can cause malignant proliferation of epithelial cells, such as HPV16, 18, 33, called high-risk type (high-risk type). Most of the viruses that cause warts are HPV types 6 and 11, which account for 70% to 90% of clinical cases, and they cause wart-like growths in the vulva and perineum. This kind of cancer is relatively unlikely. However, there is a small percentage of warts caused by high-risk types of infection.  In recent years, with the development of HPV testing technology and the promotion and popularity of colposcopy, the detection rate of cervical warts, previously thought to be relatively rare, has climbed rapidly and high-risk HPV infections of condyloma acuminata are becoming more common. I’ve shared a case with you before on Twitter where HPV 31, 51, 58, 66, 82, and 6/11 were detected in multiple high- and low-risk types from a small patch of warts on the vulva of a patient.  Unlike HPV 6 and 11, which are low-risk types, HPV 16 and 18 infections cause epithelial hyperplasia not in the form of warts, but in the form of plaques or patches, especially when the infection occurs in the female cervix. When the cervical area is externally coated with 3% glacial acetic acid, the areas infected with HPV types 16 and 18 become white patches. After persistent infection of the cervical epithelium with high-risk HPV viruses, it can develop into cancer in some people after years and decades of development. Examination of cancerous tissues removed from cervical cancer patients reveals HPV infection in about 90% or more. Of course, the occurrence of cervical cancer is a complex process, which is likely to be the result of multi-factor stimulation, but during the parasitic and replication process of high-risk HPV in epithelial cells, its DNA may integrate into the core material DNA of human epithelial cells to cause mutation of genes leading to malignant proliferation of cells is one of the factors for the occurrence of cervical cancer.  In addition to cervical cancer, high-risk HPV infection can also cause other cancers to develop years later in acromegaly that are initially benign, a medical condition known as Bowen-like papulosis, which is an in situ cancer of the vulva. Bowen-like papulosis is a flat brown or brownish-black papule on the vulva of both men and women, either solitary or multiple, usually without any discomfort.   The actual fact is that you can find a lot of people who are not able to get a lot of money for the purpose of the actual project.