I. What is fatigue? Fatigue is a subjective feeling of overwhelming and constant tiredness even after sufficient sleep, and a significant decrease in physical and mental functions that interferes with one’s ability to perform daily life functions. The fatigue of cancer patients can occur at any time and cannot be effectively improved by rest or sleep. 1. When cancer patients receive chemotherapy or radiation treatment, cells are destroyed and die, and the release of metabolic waste increases, resulting in cancer patients easily getting tired during treatment. 2. Fatigue occurs when fever, nausea, vomiting, anemia, pain, and good nutritional status occur due to treatment, resulting in abnormal metabolic changes or imbalance. 3. The fatigue will be increased when the physical activity is reduced and the sleep is disrupted due to the disease factor or treatment. Self-care for fatigue: 1. Eat more high-calorie, high-protein, fresh fruits and vegetables, and at least 3,000cc of water daily if there is no contraindication. 2, 3-5 times a week, 30-45 minutes of brisk walking, cycling, jogging, dancing and other aerobic exercise is one of the most common and effective ways to deal with fatigue. 3. Plan the necessary daily activities, set the priority of activities or postpone the non-essential activities; conserve personal energy and save physical energy, such as sitting down, avoiding bending over, using easy-to-use household appliances, putting supplies in an easily accessible place, sitting on a chair in the shower room, and using a large bath towel when drying the body. 4. According to the activity meter, appropriately increase the amount of physical activity during the day, and take a nap during the day without affecting sleep at night. 5.Use music, watching movies or reading, as well as deep breathing exercises, massage to guide the imagination to achieve relaxation, to divert the attention to fatigue.