Once diagnosed, gallbladder cysts should be treated surgically as early as possible to prevent recurrent episodes of cholangitis, leading to serious complications such as cirrhosis, carcinoma, and even cyst rupture and bleeding. The main treatment nowadays is complete removal of the gallbladder and Roux-en-Y anastomosis of the bile intestine, which has excellent clinical efficacy. When removing the gallbladder, only the cystic mucosa needs to be completely peeled off under the cystic mucosa, and complete removal of the cystic wall is not required. In patients with severe infection or perforation, external drainage of the cyst can be performed first. After the patient’s symptoms are controlled, the general condition improves, and the jaundice subsides, second-stage cystectomy and internal bile intestinal drainage can be performed. For patients with limited intrahepatic bile duct dilatation, hepatectomy of the diseased segment can be performed at the same time. In cases of dilated intrahepatic bile ducts, where the lesion involves the whole liver or has been complicated by cirrhosis, liver transplantation may be considered.