Chronic gastritis with erosion to gastric cancer takes 15-20 years, and the more recognized pathways are chronic superficial gastritis, chronic atrophic gastritis, intestinal epithelial hyperplasia, heterogeneous hyperplasia, and gastric cancer. Each stage of progression takes a different amount of time, and not every gastritis progresses to the next step; each step of progression is influenced by a variety of factors. The most common influencing factor is still H. pylori infection, so the pathway is blocked in many patients after anti-H. pylori infection treatment, which is the reason why aggressive anti-H. pylori treatment can reduce the occurrence of gastric cancer. 15-20 years is the time without any intervention, and if there is intervention some patients may not have cancer in their lifetime.