The triple therapy for chronic gastritis is a proton pump inhibitor plus two antibiotics, or bismuth plus two antibiotics. The specific choice of proton pump inhibitor or bismuth requires the patient to visit a hospital offline and choose which type of drug to use only after a specialist takes a detailed medical history and reviews the ancillary tests. The choice of antibiotics needs to be based on local antibiotic resistance and the patient’s own history of drug allergies. However, not all patients with chronic gastritis require H. pylori eradication, that is, most patients with chronic gastritis do not require triple therapy unless there is clear evidence of gastric mucosal erosion, or moderate to severe atrophy of the gastric mucosa, and a family history of gastric cancer. In addition, if the clinical symptoms of chronic gastritis are stubborn and the effect of conventional treatment is not satisfactory, triple therapy can also be recommended, but other patients with chronic gastritis are advised not to rush to eradicate HP first.