There are many accidents in life that often happen without notice. According to the survey, many people suffer from cranial defects due to an accident or a natural or man-made disaster, thus dealing a heavy blow to their health. Cranial defects are of great importance and if they are not repaired as soon as possible, they will not only have a great impact on the external appearance of the person, but also the brain tissue will easily suffer secondary injuries due to the loss of the normal cranial barrier protection, and other complications may arise. In the neurosurgical guidelines, for patients with cranial defects caused by debridement due to intracranial hypertension, generally 2-3 months after the defect, if the defect area reaches 3*3 cm or more, it meets the surgical characteristics and the patient needs to go to the hospital to be repaired by a professional surgeon. Cranial bone repair is a common surgery, the implementation of which is not difficult and can be carried out in large hospitals in general places, as long as the scalp is cut, the periosteum is bluntly separated, the bone window is completely exposed, the repair prosthesis is taken and placed in the bone window and adjusted to achieve physiological anatomical reset, and the skin is sutured layer by layer. Only the surgical approach taken is different, and the results achieved are very different. At present, the common clinical practice is titanium mesh cranial repair, but because the implant material is metal titanium, the covered repair method increases the chance of postoperative rejection infection and material exposure, which makes the repair effect not very satisfactory. At present, the peek cranial repair and plastic surgery carried out clinically can help patients achieve the dual goals of basic repair and shape shaping with good results, which is an advanced and mature repair material.