Thyroid puncture biopsy may be harmful to the body, but the harm is not great. Bleeding, nerve damage and infection may occur, but the harm can be minimized under the operation of professional doctors. 1. Bleeding: There are two blood vessels, the internal jugular vein and the common carotid artery, next to the thyroid gland. If the procedure is not done correctly, the puncture needle may mistakenly enter into these two blood vessels, resulting in bleeding or hematoma. 2. Nerve damage: there is an important nerve in the thyroid area that affects the human body’s voice, once the recurrent laryngeal nerve is damaged, the voice will be hoarse or even difficult to pronounce. 3. Infection: If the patient does not pay attention to protect the wound after puncture, it may cause wound infection and suppuration. Any surgery has certain hazards to the body, it is recommended that patients who need thyroid puncture biopsy should go to the hospital in time and operate under the guidance of the doctor, so as to avoid delaying the condition and causing adverse consequences.