Appendicitis is a common surgical emergency. Patients with appendicitis can be diagnosed by color ultrasound in addition to their symptoms and signs. Color ultrasound can effectively and accurately determine appendicitis, especially the typical appendicitis, by visualizing the enlarged appendix, the acoustic fecal stone in the appendiceal cavity, the thick wall of the appendiceal cavity, and the uneven internal echogenicity, including the hypoechoic oozing shadow around the local area. Therefore, patients with appendicitis should prefer to have an ultrasound of the right lower abdominal gyrus to further verify the possibility of appendicitis, as well as to combine the patient’s symptoms and signs with blood biochemical tests to better help the diagnosis of appendicitis.