Lung nodules of 1.6 centimeters with clear borders have a certain malignant potential and are relatively serious, so they need to be taken seriously and examined in a timely manner to determine whether treatment is needed. Whether a lung nodule is serious or not needs to be judged according to the size and shape of the nodule, as well as the smoking history and family history, etc. In general, the larger the nodule, the higher the possibility of malignancy. Generally speaking, the larger the nodule, the higher the possibility of malignancy. Lung nodules larger than 8mm should be taken seriously, and the possibility of malignancy should be considered. Malignant nodules usually have fuzzy borders and may show lobular signs, burr signs, and have blood vessels passing through the nodule. In the case of a 1.6-centimeter nodule with clear margins, the large size of the nodule suggests a higher likelihood of malignancy, even though the margins are clear. If there is also a history of smoking, second-hand smoke, family history of tumor, etc., it is necessary to improve the examination related to early lung cancer, and do minimally invasive surgery for treatment if necessary. If a lung nodule of 1.6 centimeters is found, it is recommended that the patient should go to a regular hospital in time to avoid delaying the condition.