The hand rubbing movement is one of the clinical manifestations of Parkinson’s syndrome. It is a degenerative disease of the substantia nigra and substantia nigra striata pathways that occurs in adults over middle age. 10% of patients have a family history; some patients may have similar manifestations due to encephalitis, cerebral arteriosclerosis, and traumatic brain injury. The cause of Parkinson’s disease is not well understood. It is now recognized that the cause of Parkinson’s disease is degenerative changes of nerve cells, with the main lesions in the substantia nigra and striatum. The gradual decrease in the number of nigrostriatal cells and the gradual loss of their function leads to a decrease in a substance called dopamine, which causes the above symptoms. According to the results of animal experiments and epidemiological studies, Parkinson’s disease is also considered to have a genetic relationship. The main focus is to prevent various possible causes of Parkinson’s disease manifestations. For example, actively controlling blood pressure and blood sugar and maintaining a healthy lifestyle; using drugs that may lead to pharmacological Parkinson’s syndrome sparingly or cautiously, or using atypical antipsychotic drugs as much as possible, or if they must be used, they should be closely observed. Genetic disorders are based on genetic screening and prenatal diagnosis, and if there are genetic abnormalities, pregnancy should be terminated.