Vomiting and diarrhea stomach pain is mostly considered to be caused by acute gastroenteritis or food poisoning, you can take antibiotics, antispasmodics or antidiarrheal drugs under the guidance of a doctor for the cause of the disease. 1. Acute gastroenteritis: you can take antibiotics such as penicillin, doxycycline, azithromycin, ciprofloxacin and other drugs to control inflammation. At the same time, you can also take loperamide and other drugs to treat diarrhea; belladonna tablets and other drugs to relieve gastrointestinal spasms and reduce abdominal pain; montelukast and other drugs can protect the intestinal mucosa and adsorption of toxins in the gastrointestinal tract. 2. Food poisoning: Symptomatic treatment drugs can be taken, such as abdominal pain, vomiting can be oral belladonna tablets or scopolamine tablets, dehydration symptoms can be intravenous rehydration. If it is allergic to Aspergillus food poisoning, available antihistamines such as Benadryl. So when vomiting and diarrhea stomach pain, it is recommended to go to the hospital in time to receive examination and active treatment. Due to individual differences, there is no absolute safest and most effective drug, it is recommended to follow the doctor’s instructions to standardize the use of adverse reactions to timely consultation, drug allergy is prohibited.