Persistent infections vary in terms of the cause of the illness and the time to danger, and some patients may not necessarily be at risk even if they have had a persistent infection for a long time. Some persistent infections, such as sepsis and tetanus, may be dangerous within a few days, and may be life-threatening if not treated in time or with the right medication. Some persistent infections, such as flat warts and dermatophytosis that last for a long time are not necessarily dangerous. Some patients have no conscious symptoms after infection, which can last for several years or more than a decade and the disease may not progress. Patients with persistent infections should have their lesions examined, have their blood tested, and have their bacteria cultured and drug sensitivity tested if necessary. Patients with persistent infections need to actively seek medical attention and take effective treatment measures against the infecting pathogen. Patients should not delay the condition, do not self-medication, in the physician’s consultation under the guidance of the standardized treatment.