Folic acid tablets need to be taken after a meal, and it is best to take them about half an hour after a meal. Because folic acid tablets are water-soluble vitamins, they are unstable and poorly absorbed in acidic solutions, and women have more stomach acid and a greater concentration of stomach acid on an empty stomach, so they are not suitable to take them before meals. After the patient eats and drinks water, the stomach acid will be diluted to reduce the concentration, and then after taking folic acid, a better absorption effect can be achieved. Folic acid has a certain stimulating effect on the gastrointestinal tract, and patients are prone to stomach bloating and painful discomfort when using it on an empty stomach before meals, and taking it about half an hour after meals can reduce the side effects. Especially when patients use therapeutic doses of folic acid, the dosage is large and must be chosen for use after meals. If the preventive dosage of folic acid is used during pregnancy, the amount is smaller and the stimulating effect on the gastrointestinal tract is relatively small.