There are many types of mycoplasma, and mycoplasma urealyticum is a very common type of urological mycoplasma infection. There are a significant number of mycoplasma carriers in the population without signs and symptoms, with Mycoplasma urealyticum being the most common. The treatment of Mycoplasma urealyticum mainly includes the following cases: 1. positive for Mycoplasma urealyticum but no symptoms: no need for treatment (carriers); 2. patients without symptoms after relevant treatment, only positive laboratory test results, considered as carriers of Mycoplasma urealyticum, no need to continue drug treatment; 3. men who are diagnosed with Mycoplasma urealyticum infection of the genitourinary system, it is recommended to treat couples together, treatment The treatment should be done during protected sexual intercourse; 4. Men infected with Mycoplasma urealyticum and combined with sperm abnormalities may affect fertility, it is recommended that both husband and wife treat a course of treatment at the same time. In terms of drugs, the commonly used regimen for the treatment of Mycoplasma solani infection is: 1. 100mg of doxycycline, twice a day for 7 days; 2. 1g of azithromycin, once a day, or 0.25g, once a day, the first dose of 0.5g for 5 to 7 days; 3. 500mg of levofloxacin, once a day for 7 days; 4. 400mg of moxifloxacin, once a day for 7 to 14 days . In conclusion, those who have symptoms of Mycoplasma solium infection need active anti-infection treatment, and should pay attention to avoid transmission to sexual partners. In addition, it is necessary to review after treatment, two weeks after stopping the drug by culture method and 4 weeks after stopping the drug by nucleic acid detection method.