For 1:5000 potassium permanganate solution, you need to take 1 gram of potassium permanganate and then dispense 5000 ml of water. In case of powder, you can take 1 gram of potassium permanganate and then add 5000 milliliters of warm boiled water to get a 1:5000 concentration of potassium permanganate solution. If you are using topical potassium permanganate tablets, which are commonly used in clinical practice, one tablet is 0.1 g. For each tablet used, you need to add 500 ml of water. Sitz baths with 1:5000 potassium permanganate solution are mainly used clinically for the treatment of perianal diseases and for cleaning small ulcers. When the concentration of potassium permanganate solution is too high, it will damage the skin and may cause redness, swelling, pain, itching and so on, so the concentration of the medicine needs to be strictly controlled in the process of use. Patients are advised to prepare potassium permanganate solution under the guidance of a professional doctor in advance to avoid the risk of medication.