If you are a patient with hepatitis B and meet the indications for antiviral therapy, follow your specialist’s advice and undergo antiviral therapy. Here I mainly want to remind patients taking nucleoside analogs to pay attention to the following points: 1. After you have taken lamivudine or adefovir, or tebivudine, or entecavir, remember to bring to the hospital for regular rechecks of liver function, HBV-DNA and ultrasound. Take the medicine for the first month, three months, six months, to the hospital to review, the doctor can be HBV-DNA changes, to determine your long-term efficacy. Do not take the medication and think that everything is fine, and do not go to the hospital for years to review. I have a patient, drug entecavir soon HBV-DNA turn negative, after 3 years, never come to the hospital to review, until one day, pain in the liver area, jaundice before coming to the hospital, a check is actually advanced liver cancer. Some drugs can be adjusted in time when the efficacy is not good. Take adefovir to check kidney function regularly, take tibivudine to check creatine kinase regularly, some individual patients will have abnormalities of the above indexes. 2, do not think that HBV-DNA turn negative, you can stop the drug, or some listen to the advice of others, eat and stop, or every other day to eat 1 tablet. This is very likely to cause deterioration of the condition or virus mutation. So far this year, we have admitted a number of patients who stopped taking medication on their own, some of them are in financial difficulties, and some of them are suffering from other diseases, and they stopped taking medication on the advice of non-specialist doctors. As a result, the patients’ conditions worsened, and some of them developed into severe hepatitis and died. Therefore, if you have any questions, you should consult with a specialist doctor, who will give you a detailed explanation. 3, patients with cirrhosis can be in the liver function is normal, serving Chinese medicines such as soft liver pill to soften the knot.