Clinically, the change of weight of diabetic patients can appear the symptom of losing weight first and then gaining weight later, because before the onset of diabetes, high blood sugar in the body causes the accelerated decomposition of fat, which can lead to weight loss, and patients are often accompanied by symptoms of excessive drinking, excessive urination and excessive eating. After regular glucose-lowering treatment, the patient’s abnormal sugar metabolism is corrected and the breakdown of fat is inhibited, and the patient can often regain weight. If the patient’s diet is not strictly controlled during the treatment process, consuming too much high-calorie and high-fat food and too little activity, weight gain will often occur. Weight gain is also related to the type of glucose-lowering drugs applied, such as insulin and oral glucose-lowering drugs that promote insulin secretion, which can also lead to weight gain when the diet is not strictly controlled.