Indirect bilirubin 18.4μmoL/L is high, if it is physiologically high, it does not matter, if it is pathologically high (such as liver disease, biliary tract disease, hemolytic disease, etc.), it may be important. 1. Physiological high: for example, high indirect bilirubin caused by excessive alcohol consumption, frequent late-night work and lack of sleep, this situation does not matter, after abstaining from alcohol, regular work and rest, and maintain sufficient sleep, generally can be gradually restored to normal. 2. Pathologically high bilirubin: (1) Liver disease, resulting in liver function damage will appear indirectly high bilirubin, most commonly seen in viral hepatitis, cirrhosis, acute hepatic necrosis, etc., this situation is important. (2) Biliary tract diseases: such as gallstones, bile duct cancer, etc. cause high indirect bilirubin, which is important. (3) Hemolytic disease: the occurrence of hemolysis causes high indirect bilirubin, which is also a critical disease. If the indirect bilirubin is high, it is recommended to consult a doctor as soon as possible to find out the cause, and if it is pathologically high, it is recommended to treat it as soon as possible.