The American Kidney Foundation’s 2002 “Clinical Practice Guidelines for Chronic Kidney Disease” states that chronic kidney disease (CKD) can be diagnosed with one of the following abnormalities: (1) kidney injury for ≥3 months: abnormal urine composition, or abnormal imaging, or abnormal pathology; with or without abnormal glomerular filtration rate (GFR); (2) GFR < 60 ml/ (min?1.73 m2 ) for ≥3 months with or without evidence of kidney injury. GFR abnormalities; ②GFR < 60 ml/ (min?1.73 m2 ) ≥ 3 months with or without evidence of kidney injury. Second, glomerular filtration rate (GFR) commonly used measurement method 1, laboratory test method to calculate GFR value: Ccr (ml / min) = urine creatinine ÷ serum creatinine X 24-hour urine volume (ml) ÷ 14402, formula to calculate GFR value: Ccr (ml / min) = (140 - age) × 88.4 × weight (kg) ÷ 72 ÷ serum creatinine (μmol/L) (Note: female patients then × 0.85) (Female patients then × 0.85) III. Hazards of chronic kidney disease 1. If chronic kidney disease is not effectively treated, they will all eventually develop into end-stage renal disease and must rely on renal replacement therapy: that is, hemodialysis, peritoneal dialysis or kidney transplantation to maintain life. 2. Chronic kidney disease is also an important cause of high morbidity and mortality of hypertension and cardiovascular diseases. IV. Prevention and treatment strategies for chronic kidney disease American Kidney Foundation's recommendations for chronic kidney disease (CKD) staging methods and prevention and treatment goals staging characteristics glomerular filtration rate GFR (ml/min) prevention and treatment goals and measures: 1. with kidney disease, GFR normal >90 CKD diagnosis and treatment, alleviate symptoms, slow down the progression of CKD; 2. Reduce the risk of cardiovascular disease; 3, moderate reduction of GFR 30-59 slow down the progression of CKD, assessment, treatment of complications; 4, severe reduction of GFR 15-29 comprehensive treatment, pre-dialysis preparation; 5, uremic syndrome.