Fanconi syndrome: A variety of etiologies lead to proximal tubular reabsorption dysfunction, loss of large amounts of glucose, amino acids, phosphate and bicarbonate in the urine, resulting in acidosis, electrolyte disorders (hypokalemia, hyponatremia, hypophosphorus), rickets and growth retardation. Clinical manifestations: 1, proximal renal tubular acidosis. 2, rickets, growth retardation. 3, irritable thirst, polyhydration, polyuria, dehydration. 4.All-amino acid urine with normal plasma amino acid concentration; positive urine glucose with normal blood glucose. 5.Electrolyte disorders: low blood potassium, high blood chloride, low blood calcium, low blood phosphorus, low blood sodium, high urinary potassium, high urinary phosphorus. 6.Mild-moderate renal tubular proteinuria. 7, Corresponding clinical manifestations of secondary diseases.