Because of the danger of GERD, once detected one should seek medical attention promptly, choose the correct treatment plan under the guidance of a doctor, and follow up regularly during treatment to adjust the treatment plan according to the efficacy. Proton pump inhibitors (PPI) are the first choice for the treatment of GERD. They are safe and efficient and can provide rapid relief of symptoms and promote healing of the damaged mucosa. Its disadvantage is that it cannot remove the disease at its root, so symptoms tend to recur after stopping the medication, which must be used for a long time, and the effect of medication is not obvious in some patients. In addition, if patients develop extraesophageal symptoms such as cough and asthma, the effect of drug treatment is limited. Surgical treatment, represented by fundoplication, has the same short-term effect as PPI, while in the long term, it is better than medication because it can address the root cause of reflux. In the past, surgery required large abdominal incisions, which were often too frightening for patients to accept. With the development of laparoscopic technology, the surgery can now be done laparoscopically with only 4-5 small incisions in the abdomen, similar to the well-known laparoscopic cholecystectomy, with fast recovery and less pain. Currently, surgery for GERD is very popular in Western countries, and in the United States, it is second only to laparoscopic cholecystectomy in terms of the number of cases performed, and is the gold standard procedure for the treatment of this disease.