Not all patients with advanced uremia necessarily need kidney transplantation. For most patients with advanced uremia, kidney transplantation is the best treatment that can give patients a near normal quality of life. However, it is difficult for the general public to afford it because, firstly, it is more difficult to get a kidney source, and secondly, the cost is higher. Also certain patients, such as those who have a relatively short life expectancy and are not suitable for kidney transplantation, or those who have a weaker constitution and can hardly tolerate the surgery, or those who cannot tolerate immunosuppressive anti-rejection therapy, are also not suitable for kidney transplantation. Most uremic patients can have a life expectancy of more than 10 years or even 30-40 years through regular and adequate hemodialysis or peritoneal dialysis. Therefore, even if they do not go into kidney transplantation, they can still obtain a longer survival time.