Renal cortical necrosis is a rare form of kidney tissue death that affects only part or all of the outer layer (cortex) of the kidney and not the inner layer (medulla). Renal cortical necrosis can occur at any age. About 10% of cases occur in infants and children. More than half of the newborns with cortical necrosis are delivered with abrupt placental separation (placental abruption); the other most common cause is bacterial infection of the blood stream (sepsis). In children, cortical necrosis can be followed by infection, dehydration, shock, or hemolytic uremic syndrome. In adults, bacterial sepsis causes cortical necrosis in about 1/3 of all cases. Screening for cortical necrosis A complex sensory examination includes a skin localization sensory examination, a two-point discrimination sensory examination, a pictorial sensory examination, and a solid sensory examination. These sensations are the result of brain synthesis, analysis and judgment, so they are also called cortical sensations. The following symptoms need to be distinguished from each other 1. thinning of the cortex of both kidneys: chronic glomerulonephritis is the final stage in the development of different types of glomerulonephritis. The lesion is characterized by a large number of glomeruli with vitreous changes and sclerosis, also known as chronic sclerosing glomerulonephritis. To the naked eye, both kidneys are reduced in size and have a diffuse, fine-grained surface. The cortex is thin and the medulla is not well defined. There is an increase in fat around the renal pelvis. The gross lesion of chronic nephritis is called secondary granular consolidation kidney. 2, acute renal failure: the pathogenesis of acute renal failure is complex, is a clinical syndrome caused by a variety of factors, the etiology of classification is not yet a perfect classification method, according to the customary division of pre-renal, renal, post-renal acute renal failure.