Azithromycin can be taken in early pregnancy. Azithromycin is a new type of macrolide antibiotic with antibacterial activity against a variety of aerobic and anaerobic Gram-positive cocci, and also inhibits many important aerobic and anaerobic Gram-negative bacilli, as well as Mycoplasma pneumoniae and Chlamydia pneumoniae. It is mainly used for lower respiratory tract infections such as upper respiratory tract infections, bronchitis and pneumonia caused by sensitive bacteria, as well as skin and soft tissue infections, and simple genital infections with Chlamydia trachomatis. It has few adverse effects, mainly gastrointestinal symptoms, such as diarrhea, epigastric discomfort, nausea, vomiting, and occasionally transient transaminase elevation. Azithromycin is classified as a Class B drug by the U.S. Food and Drug Administration and Maternal Safety Medication, and its use by pregnant women will not lead to fetal malformation and fetal growth and developmental restriction. Therefore, it can be used in early pregnancy, but pregnant women should try to avoid the use of the drug during pregnancy.