Which is more serious, dry syndrome or rheumatoid arthritis, depends on the patient’s own situation and cannot be generalized. 1. Dry Syndrome: Patients with dry syndrome will have symptoms such as swollen joints, dry mouth and eyes, resulting in dry mouth, dry nose, dry eyes, etc. In severe cases, it can lead to interstitial lung disease, renal tubular acidosis and other organ damage, which can jeopardize the health of patients. In severe cases, it can lead to interstitial lung lesions, renal tubular acidosis and other organ damage, which can be life-threatening. 2. Rheumatoid arthritis: rheumatoid arthritis is mainly symmetrical multi-joint swelling and pain as the main clinical manifestations, in the later stages of the disease is serious, will lead to deformation of the joints, seriously affecting the patient’s quality of life, but also may lead to the patient’s life can not take care of themselves. In severe cases, it may lead to interstitial lung disease, pulmonary hypertension and other related diseases, which may be life-threatening. Whether it is dry syndrome or rheumatoid arthritis, only early treatment, control the progress of the disease, usually not very serious, if the disease is not timely treatment, the involvement of multiple organs, multiple systems is more serious. Therefore, which of the two diseases is more serious depends on the patient’s own situation. Patients with dry syndrome and rheumatoid arthritis are advised to consult with the rheumatology and immunology department of a regular hospital for detailed consultation and standardized diagnosis and treatment in accordance with medical advice.