The causes of chest tightness and occasional pain are physiologic and pathologic. Pathologic factors include coronary heart disease, emphysema, etc. Treatment includes medication such as anticoagulants and surgery. 1. Physiological factors: prolonged overwork, high mental tension, anxiety and depression, long-term sleep deprivation can lead to chest tightness and chest pain. Active physical exercise, good habits of work and rest, and maintaining a healthy state of mind can effectively alleviate the symptoms. 2. Pathological factors (1) Coronary heart disease: Coronary heart disease leads to a decline in heart function, causing chest pain and chest tightness with shortness of breath. Commonly used drugs include aspirin, nitroglycerin, etc. If the condition is serious, coronary artery bypass grafting is feasible. (2) Emphysema: often lead to exertional shortness of breath and accompanied by chest tightness and chest pain, treatment methods include drug therapy such as salbutamol, ipratropium bromide, etc., conservative treatment is ineffective feasible lung transplantation. The choice of medication should be made under the guidance of a doctor. When symptoms of chest tightness occur, go to the hospital immediately.